Julien Paccou

Contact, P

Contact:

julien.paccou@chru-lille.fr

Research Unit(s):

MABLab ULR 4490 – Department of Rheumatology – Lille University Hospital – University Lille

Team-project:

Clinical approach of BMAT

Research discipline:

Medical and Health Sciences: Bone Marrow Adiposity, Osteoporosis, Obesity, Bariatric surgery, Weight loss

Expertise:

Clinical research
Epidemiology
Rheumatology

Projects:

As principal investigator

ADIMOS: NCT03219125 Bone Marrow Adiposity and Fragility Fractures in Postmenopausal Women: The ADIMOS Case-Control Study.
ADIMOS-OB: NCT05005039 Bone Marrow Adiposity and Bariatric Surgery-mediated Bone Loss

Activities

Executive Board Member of the BMAS (Bone Marrow Adiposity Society) as secretary since 2024
Member of the Committee of Scientific Advisors (CSA) of the International Osteoporosis Foundation (IOF) since 2015
Member of the Capture The Fracture (CTF) Steering committee of the International Osteoporosis Foundation (IOF) since 2023
Member of the ECTS (European Calcified Tissue Society) clinical action group since 2022
Member of the Scientific Board Advisory (SBA) of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) since 2016
Board Member of the GRIO (Groupe de Recherche et d’information sur les Ostéoporoses) since 2017, that is the French osteoporosis society member of the IOF
Reviewer for the Journal of Bone Mineral Research, Journal of Clinical Endocrinology and Metabolism, Bone, Osteoporosis international, Calcified Tissue International, Rheumatology, The journal of Rheumatology, Arthritis Care Research, Arthritis Rheumatology, British Medical Bulletin…

Publications in 2023

Beekman KM, Duque G, Corsi A, Tencerova M, Bisschop PH, Paccou J. Osteoporosis and Bone Marrow Adipose Tissue. Curr Osteoporos Rep. 2023 Feb;21(1):45-55. doi: 10.1007/s11914-022-00768-1. Epub 2022 Dec 19. PMID: 36534306.
2: Biver E, Herrou J, Larid G, Legrand MA, Gonnelli S, Annweiler C, Chapurlat R, Coxam V, Fardellone P, Thomas T, Lecerf JM, Cortet B, Paccou J. Dietary recommendations in the prevention and treatment of osteoporosis. Joint Bone Spine. 2023 May;90(3):105521. doi: 10.1016/j.jbspin.2022.105521. Epub 2022 Dec PMID: 36566976.

3: Jauffret C, Périchon R, Lamer A, Cortet B, Chazard E, Paccou J. Association Between Sarcopenia and Fracture Risk in a Population From the UK Biobank Database. J Bone Miner Res. 2023 Oct;38(10):1422-1434. doi: 10.1002/jbmr.4884. Epub 2023 Aug 3. PMID: 37458535.
Paccou J, Philippoteaux C, Cortet B, Fardellone P. Effectiveness of fracture liaison services in osteoporosis. Joint Bone Spine. 2023 Sep;90(5):105574. doi: 10.1016/j.jbspin.2023.105574. Epub 2023 Apr 18. PMID: 37080285.
Anastasilaki E, Paccou J, Gkastaris K, Anastasilakis AD. Glucocorticoid-induced osteoporosis: an overview with focus on its prevention and management. Hormones (Athens). 2023 Dec;22(4):611-622. doi: 10.1007/s42000-023-00491-1. Epub 2023 Sep 27. PMID: 37755658.
Anastasilakis AD, Naciu AM, Yavropoulou MP, Paccou J. Risk and management of osteoporosis due to inhaled, epidural, intra-articular or topical glucocorticoids. Joint Bone Spine. 2023 Dec;90(6):105604. doi: 10.1016/j.jbspin.2023.105604. Epub 2023 Jul 1. PMID: 37399940.
Herrou J, Mabilleau G, Lecerf JM, Thomas T, Biver E, Paccou J. Narrative Review of Effects of Glucagon-Like Peptide-1 Receptor Agonists on Bone Health in People Living with Obesity. Calcif Tissue Int. 2023 Nov 24. doi:10.1007/s00223-023-01150-8. Epub ahead of print. PMID: 37999750.
Anastasilakis AD, Makras P, Paccou J, Bisbinas I, Polyzos SA, Papapoulos SE. Similarities and Differences in the Management of Patients with Osteoporotic Vertebral Fractures and Those with Rebound-Associated Vertebral Fractures Following Discontinuation of Denosumab. J Clin Med. 2023 Sep 10;12(18):5874. doi: 10.3390/jcm12185874. PMID: 37762815; PMCID: PMC10532339.
Philippoteaux C, Marty-Ane A, Cailliau E, Labreuche J, Philippe P, Cortet B, Paccou J, Flipo RM, Letarouilly JG. Characteristics Of Difficult-To-Treat Psoriatic Arthritis: A Comparative Analysis. Semin Arthritis Rheum. 2023 Dec;63:152275. doi: 10.1016/j.semarthrit.2023.152275. Epub 2023 Oct 5. PMID: 37852155.
Tencerova M, Duque G, Beekman KM, Corsi A, Geurts J, Bisschop PH, Paccou J. The Impact of Interventional Weight Loss on Bone Marrow Adipose Tissue in People Living with Obesity and Its Connection to Bone Metabolism. Nutrients. 2023 Oct 29;15(21):4601. doi: 10.3390/nu15214601. PMID: 37960254; PMCID: PMC10650495.
Philippoteaux C, Delepine T, Cailliau E, Philippe P, Taisne N, Pascart T, Cortet B, Paccou J, Flipo RM, Letarouilly JG. Characteristics of difficult-to-treat axial spondyloarthritis: Results of a real-world multicentric study. Joint Bone Spine. 2023 Nov 29;91(2):105670. doi: 10.1016/j.jbspin.2023.105670. Epub ahead of print. PMID: 38036061.
Badr S, Cotten A, Mentaverri R, Lombardo D, Labreuche J, Martin C, Hénaut L, Cortet B, Paccou J. Relationship between bone marrow adipose tissue and kidney function in postmenopausal women. Bone Rep. 2023 Sep 8;19:101713. doi:10.1016/j.bonr.2023.101713. PMID: 37711545; PMCID: PMC10498167.
Paccou J, Badr S, Lombardo D, Khizindar H, Deken V, Ruschke S, Karampinos DC, Cotten A, Cortet B. Bone Marrow Adiposity and Fragility Fractures in Postmenopausal Women: The ADIMOS Case-Control Study. J Clin Endocrinol Metab. 2023 Sep 18;108(10):2526-2536. doi: 10.1210/clinem/dgad195. PMID: 37017011.
Badr S, Dapvril H, Lombardo D, Khizindar H, Martin C, Cortet B, Cotten A, Paccou J. Myosteatosis and bone marrow adiposity are not associated among postmenopausal women with fragility fractures. Front Endocrinol (Lausanne). 2023 Jun 19;14:1178464. doi: 10.3389/fendo.2023.1178464. PMID: 37404309; PMCID: PMC10316646.
Jauffret C, Périchon R, Lamer A, Cortet B, Chazard E, Paccou J. Association between sarcopenia and risk of major adverse cardiac and cerebrovascular events- UK Biobank database. J Am Geriatr Soc. 2023 Nov 9. doi: 10.1111/jgs.18664. Epub ahead of print. PMID: 37945290.
Courtalin M, Bertheaume N, Badr S, During A, Lombardo D, Deken V, Cortet B, Clabaut A, Paccou J. Relationships between Circulating Sclerostin, Bone Marrow Adiposity, Other Adipose Deposits and Lean Mass in Post-Menopausal Women. Int J Mol Sci. 2023 Mar 21;24(6):5922. doi: 10.3390/ijms24065922. PMID: 36982995; PMCID: PMC10053867.
Desvages A, Hives F, Deprez X, Pierache A, Béhal H, Flipo RM, Paccou J. Usefulness of 18F-Fluorodeoxyglucose Positron Emission Tomography in Diagnosing Polymyalgia Rheumatica and Large-Vessel Vasculitis: A Case-Control Study. J Clin Med. 2023 Apr 13;12(8):2844. doi: 10.3390/jcm12082844. PMID: 37109181; PMCID: PMC10141365.
Courtalin M, Verkindt H, Oukhouya Daoud N, Ramdane N, Cortet B, Pattou F, Paccou J. An Evaluation of the Implementation of the European Calcified Tissue Society Recommendations on the Prevention and Treatment of Osteoporosis Secondary to Bariatric Surgery. Nutrients. 2023 Feb 17;15(4):1007. doi: 10.3390/nu15041007. PMID: 36839365; PMCID: PMC9964124.